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DBCO-(PEG)3-VC-PAB-MMAE
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-(PEG)3-VC-PAB-MMAE is made by MMAE conjugated to DBCO-(PEG)3-vc-PAB linker. Monomethyl auristatin E (MMAE), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. 靶点活性 Auristatin分子量 1613.97 分子式 C86H124N12O18 CAS No. T17817存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度
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DBCO-S-S-PEG3-biotin
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-S-S-PEG3-biotin is a cleavable reagent for introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label. PEG Linkers can be used in the synthesis of PROTACs. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].别名 生物素-PEG3-二硫-DBCO 纯度
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DBCO-NHCO-PEG4-NHS ester
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.分子量 649.69 分子式 C34H39N3O10 CAS No. 2100306-58-7存储 Powder: -20°C for 3 years
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DBCO-C3-PEG4-NH-Boc
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-C3-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs Alkyl/ether 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 709.83 分子式 C38H51N3O10 CAS No. T1
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DBCO-C2-PEG4-NH-Boc
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-C2-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs Alkyl/ether 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 695.8 分子式 C37H49N3O10 CAS No. T17
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DBCO-PEG3-SS-NHS ester
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-PEG3-SS-NHS ester is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 697.82 分子式 C34H39N3O9S2 CAS No. T17791存储 Powder: -20°C for 3 years In
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Gly-Gly-Gly-PEG4-DBCO
作者：德尔塔 日期：2022-08-31
产品描述 Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 694.77 分子式 C35H46N6O9 CAS No. 2353409-80-8存储 Powder: -20°C for 3 years
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DBCO-NHCO-C4-NHS ester
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-NHCO-C4-NHS ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 Alkyl-Chain 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 501.53 分子式 C28H27N3O6 CAS No. T17757存储
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DBCO-NHCO-PEG4-NH-Boc
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.分子量 623.74 分子式 C34H45N3O8 CAS No. 1255942-12-1存储 Powder: -20°C for 3 years In solvent:
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LG-PEG10-click-DBCO-Oleic
作者：德尔塔 日期：2022-08-31
产品描述 LG-PEG10-click-DBCO-Oleic is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 1407.68 分子式 C70H114N6O23 CAS No. T18071存储
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DBCO-NHCO-PEG2-NHS ester
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-NHCO-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs Alkyl/ether 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 561.58 分子式 C30H31N3O8 CAS No.
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DBCO-NHCO-PEG13-NHS ester
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-NHCO-PEG13-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs Alkyl/ether 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 1046.16 分子式 C52H75N3O19 CAS No.
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DBCO-NHCO-PEG5-NHS ester
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-NHCO-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 693.74 分子式 C36H43N3O11 CAS No. 1378531-80-6存储
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DBCO-Val-Cit-PABC-PNP
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-Val-Cit-PABC-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 859.92 分子式 C46H49N7O10 CAS No. T17816存储 Powder: -20°C for 3 years In solvent:
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DBCO-Val-Cit-PABC-OH
作者：德尔塔 日期：2022-08-31
产品描述 DBCO-Val-Cit-PABC-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 694.82 分子式 C39H46N6O6 CAS No. T17815存储 Powder: -20°C for 3 years In solvent: -8
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