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Mal-Sulfo-DBCO
作者:德尔塔 日期:2022-08-30
产品描述 Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 578.59 分子式 C28H26N4O8S CAS No. 2028281-86-7存储 Powder: -20°C for 3 years In solvent: -
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DBCO-PEG4-TAMRA
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-PEG4-TAMRA, contains a DBCO group, is a PEG-based TARMA dye. The TAMRA dye is a dye widely used in oligonucleotide labeling. 靶点活性 TARMA Dye 体外活性 DBCO reacts with azide functionalized compounds or biomolecules without catalyst to form a stable triazole linkage, which is an ideal alternative to copper intolerant applications.分子量 936.06 分子式 C54H57N5O10 CAS No. 1895849-41-8存储
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DBCO-PEG4-amine
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-PEG4-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-PEG4-amine can be used in the synthesis of FPM-PEG4-DBCO (a homobifunctional azide-to-azide cross-linker)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.分子量 523.62 分子式 C29H37N3O6 CAS No. 1840886-10-3存储
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BDP FL DBCO
作者:德尔塔 日期:2022-08-30
产品描述 BDP FL DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 550.41 分子式 C32H29BF2N4O2 CAS No. 2093197-94-3存储 Powder: -20°C for 3 years In solvent: -8
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DBCO-PEG12-TCO
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-PEG12-TCO contains a DBCO and a TCO moiety. 靶点活性 Others 体外活性 DBCO reacts with azide functionalized compounds or biomolecules without a catalyst to form a stable triazole linkage.分子量 1028.23 分子式 C54H81N3O16 CAS No. 2055022-06-3存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years
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DBCO-PEG1
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 PEGs 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 348.4 分子式 C21H20N2O3 CAS No. 1839049-33-0存储
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Methyltetrazine-DBCO
作者:德尔塔 日期:2022-08-30
产品描述 Methyltetrazine-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Non-cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 683.73 分子式 C34H33N7O7S CAS No. 1802238-48-7存储 Powder: -20°C for 3 years In
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Fluorescein-DBCO
作者:德尔塔 日期:2022-08-30
产品描述 Fluorescein-DBCO is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Non-cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].分子量 665.71 分子式 C39H27N3O6S CAS No. 2054339-00-1存储 Powder: -20°C for 3 years In solv
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DBCO-Biotin
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-Biotin is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 Alkyl-Chain 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 502.63 分子式 C28H30N4O3S CAS No. 1418217-95-4存储
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DBCO-Maleimide
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.分子量 427.45 分子式 C25H21N3O4 CAS No. 1395786-30-7存储 Powder: -20°C for 3 years In solvent: -80°C
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Oleic-DBCO
作者:德尔塔 日期:2022-08-30
产品描述 Oleic-DBCO is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 靶点活性 Alkyl-Chain 体外活性 PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].分子量 540.78 分子式 C36H48N2O2 CAS No. 2279951-78-7存储
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DBCO-amine
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. 靶点活性 Cleavable 体外活性 ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.纯度 97.73% 分子量 276.33 分子式 C18H16N2O CAS No. 1255942-06-3存储
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DBCO-Cy3
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-Cy3 (DBCO-Sulfo-Cy3) is the derivative of Cyanine3 fluorophore, a pH insensitive from pH (4-10) orange fluorescent dye (excitation maximum: 555 nm; emission maximum: 580 nm). 靶点活性 Orange fluorescent dye别名 DBCO-Sulfo-Cy3 分子量 983.18 分子式 C50H54N4O11S3 CAS No. 1782950-79-1存储 Powder: -20°C for 3 years
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Cy5-DBCO
作者:德尔塔 日期:2022-08-30
产品描述 Cy5-DBCO (DBCO-Sulfo-Cy5) is a near-infrared (NIR) red fluorescent dye (λabs: 646 nm, λem: 670 nm). Cy5-DBCO is not suitable for staining intracellular components of the permeabilized cells because it may exhibit a high background. 靶点活性 Red fluorescent dye别名 DBCO-Sulfo-Cy5 分子量 1009.22 分子式 C52H56N4O11S3 CAS No. 1564286-24-3存储 P
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DBCO-acid
作者:德尔塔 日期:2022-08-30
产品描述 DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester, and drug-linker conjugates DBCO-PEG-MMAE[1]. 靶点活性 Cleavable分子量 305.33 分子式 C19H15NO3 CAS No. 1353016-70-2存储 Powder: -20°C for 3 years In solvent: -80°C for 2 years 溶解度 DMSO: 100 mg/mL (327.51 mM), Need ultrasonic