【产品介绍】：

产品名称 FG-4592 英文名称 FG-4592 规格或纯度 ≥98% 别名 FG4592;FG 4592;N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine;[[(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]amino]acetic acid 英文别名 FG4592;FG 4592;N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine;[[(4-Hydroxy-1-methyl-7-phenoxyisoquinolin-3-yl)carbonyl]amino]acetic acid 运输条件 冰袋运输 生化机理 FG-4592 is an inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase currently in clinical development for the treatment of anemia. FG-4592 stabilizes the activities of HIF, a cytosolic transcription factor, leading to activation of the genes associated with erythropoiesis, including erythropoietin and enzymes involved in iron metabolism. A phase II clinical trial of FG-4592 has been competed in the treatment of chronic kidney disease.CAS编号 808118-40-3 溶解性 DMSO >70 mg/mL Water <1 mg/mL Ethanol <1 mg/mL 储存温度 2-8°C 分子量 352.34 分子式 C19H16N2O5 PubChem CID 11256664