CAS:761437-28-9|TAE226(NVP-TAE226)
【产品介绍】:
产品名称 Salinomycin 英文名称 Salinomycin 应用 A polyether potassium ionophore. 规格或纯度 ≥98% 别名 盐霉素 英文别名 Procoxacin;Coxistac;Antibiotic 61477;(2R)-2-{(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-{(2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-Ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13- en-9-yl}-3-hydrox 运输条件 超低温冰袋运输 生化机理 Salinomycin is a polyether potassium ionophore antibiotic, which promotes cation movement across biological membranes via exchange-diffusion. As a result of this cation exchange, the transmembrane gradients are altered, which leads to changes in cellular function and metabolism. In addition, Salinomycin acts as a chelating agent towards monovalent cations such as sodium and potassium ions. Alternate studies sμggest that Salinomycin selectively inhibits cancer stem-like cells.CAS编号 761437-28-9 溶解性 DMSO 94 mg/mL Water <1 mg/mL Ethanol <1 mg/mL 储存温度 储存温度-20°C 分子量 468.94 分子式 C23H25ClN6O3 PubChem CID 9934347