【产品介绍】：

产品名称 Neratinib (HKI-272) 英文名称 Neratinib (HKI-272) 应用 A potent and selective inhibitor of EGFR and HER2 规格或纯度 ≥99% 别名 来那替尼 生化机理 Neratinib is a potent and selective inhibitor of EGFR and Neu(HER2) (IC50 = 92 nM and 59 nM, respectively) by preventing phosphorylation of these proteins by their respective kinases. Neratinib displays activity against a variety of cancer cell lines, including A431, 3T3, and MDA-MB-435. Neratinib is an inhibitor of c-Src and Flk-1.CAS编号 698387-09-6 敏感性 比旋光度 折光率 熔点 凝固点 沸点 溶解性 Soluble in DMSO (2 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C). 储存温度 储存温度-20°C Reaxys-RN RTECS MDL号 分子量 557.04 FEMA编号 分子式 C30H29ClN6O3 EC号 Smiles PubChem CID 9915743