【产品介绍】：

产品名称 Brivanib (BMS-540215) 英文名称 Brivanib (BMS-540215) 应用 An ATP-competitive inhibitor against VEGFR-2, Flk-1, VEGFR-1 and FGFR-1 规格或纯度 ≥98% 别名 酪氨酸激酶抑制剂 生化机理 Brivanib is an ATP-competitive inhibitor against human VEGFR-2 and mouse Flk-1 with IC50 of 25 nM and 89 nM, respectively. Brivanib also inhibits VEGFR-1 and FGFR-1 with IC50 of 0.38 and 0.148 μM. Brivanib displays antitumor activities in H3396 xenograft. This compound completely inhibits the tumor growth, with TGI of 85% and 97%, respectively.CAS编号 649735-46-6 溶解性 Soluble in DMSO (74 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (3 mg/ml at 25 °C). 储存温度 储存温度-20°C 分子量 370.39 分子式 C19H19FN4O3 PubChem CID 11234052